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The arginine-rich N-terminal domain of ROP18 is necessary for vacuole targeting and virulence of Toxoplasma gondii

Toxoplasma gondii uses specialized secretory organelles called rhoptries to deliver virulence determinants into the host cell during parasite invasion. One such determinant called rhoptry protein 18 (ROP18) is a polymorphic serine/threonine kinase that phosphorylates host targets to modulate acute v...

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Bibliografiske detaljer
Main Authors: Fentress, Sarah J., Steinfeldt, Tobias, Howard, Jonathan C., Sibley, L. David
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3683533/
https://ncbi.nlm.nih.gov/pubmed/22906355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cmi.12022
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