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Prediction of Toxoplasma gondii virulence factor ROP18 competitive inhibitors by virtual screening
BACKGROUND: Rhoptry protein 18 (ROP18) is a key virulence factor of Toxoplasma gondii. The host’s immune responses mediated by immune-related GTPases (IRGs) could be blocked by ROP18’s kinase activity. ROP18 also interacts with various substrates, such as activating transcription factor 6 beta (ATF6...
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| Izdano u: | Parasit Vectors |
|---|---|
| Glavni autori: | , , , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
BioMed Central
2019
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6416898/ https://ncbi.nlm.nih.gov/pubmed/30867024 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13071-019-3341-y |
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