Prediction of Toxoplasma gondii virulence factor ROP18 competitive inhibitors by virtual screening

BACKGROUND: Rhoptry protein 18 (ROP18) is a key virulence factor of Toxoplasma gondii. The host’s immune responses mediated by immune-related GTPases (IRGs) could be blocked by ROP18’s kinase activity. ROP18 also interacts with various substrates, such as activating transcription factor 6 beta (ATF6...

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Bibliografiska uppgifter
I publikationen:Parasit Vectors
Huvudupphovsmän: Yin, Kun, Zhao, Guihua, Xu, Chao, Qiu, Xiao, Wen, Biwei, Sun, Hui, Liu, Gongzhen, Liu, Ye, Zhao, Qingsong, Wei, Qingkuan, Huang, Bingcheng, Yan, Ge, Cao, Jianping
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2019
Ämnen:
Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6416898/
https://ncbi.nlm.nih.gov/pubmed/30867024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13071-019-3341-y
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