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The arginine-rich N-terminal domain of ROP18 is necessary for vacuole targeting and virulence of Toxoplasma gondii

Toxoplasma gondii uses specialized secretory organelles called rhoptries to deliver virulence determinants into the host cell during parasite invasion. One such determinant called rhoptry protein 18 (ROP18) is a polymorphic serine/threonine kinase that phosphorylates host targets to modulate acute v...

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Detalhes bibliográficos
Main Authors: Fentress, Sarah J., Steinfeldt, Tobias, Howard, Jonathan C., Sibley, L. David
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3683533/
https://ncbi.nlm.nih.gov/pubmed/22906355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cmi.12022
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