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Deciphering HIC1 control pathways to reveal new avenues in cancer therapeutics

INTRODUCTION: The tumor suppressor gene HIC1 (Hypermethylated in Cancer 1) which encodes a transcriptional repressor with multiple partners and multiple targets is epigenetically silenced but not mutated in tumors. HIC1 has broad biological roles during normal development and is implicated in many c...

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Hlavní autoři: ROOD, Brian R., LEPRINCE, Dominique
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3683369/
https://ncbi.nlm.nih.gov/pubmed/23566242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/14728222.2013.788152
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