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Destruction of a Destructor: A New Avenue for Cancer Therapeutics Targeting the Wnt Pathway
A new study in Nature has identified a small molecule inhibitor for the oncogenic Wnt/β-catenin pathway that is responsible for many human cancers. This inhibitor targets an unsuspected cellular enzyme, Tankyrase, which controls the destruction of a β-catenin destructor.
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2010
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2861491/ https://ncbi.nlm.nih.gov/pubmed/20008332 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jmcb/mjp040 |
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