Targeting the Wnt pathway in cancer

The Wnt pathway is an evolutionarily conserved signaling network that is critical for mammalian development and adult tissue maintenance, and, importantly, hyperactivated in most human cancers. Almost two decades of study has confirmed that Wnt signaling is necessary and sufficient for cancer pathog...

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Bibliographic Details
Main Authors: Goss, Kathleen Heppner., Kahn, Michael.
Format: Livro
Language:Inglês
Published: Springer New York, 2011
Subjects:
Neoplasias Terapia.
Neoplasias Genética.
Neoplasias Pesquisa.
Proteínas Wnt.
Via de sinalização Wnt.
Transdução de sinais.
Reparo gênico alvo-dirigido Métodos.
Oncologia.
Online Access:https://minerva.ufrj.br/F/?func=direct&doc_number=000918312&local_base=UFR01
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