Constitutive activation of the Wnt canonical pathway in mantle cell lymphoma

Aberrations of the Wnt canonical pathway (WCP) are known to contribute to the pathogenesis of various types of cancer. We hypothesize that these defects may exist in mantle cell lymphoma (MCL). Both the upstream and downstream aspects of WCP were examined in MCL cell lines and tumors. Using WCP-spec...

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Detalhes bibliográficos
Main Authors: Gelebart, Pascal, Anand, Mona, Armanious, Hanan, Peters, Anthea C., Dien Bard, Jennifer, Amin, Hesham M., Lai, Raymond
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2008
Assuntos:
Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597612/
https://ncbi.nlm.nih.gov/pubmed/18787224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-02-139212
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