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Constitutive activation of the Wnt canonical pathway in mantle cell lymphoma

Aberrations of the Wnt canonical pathway (WCP) are known to contribute to the pathogenesis of various types of cancer. We hypothesize that these defects may exist in mantle cell lymphoma (MCL). Both the upstream and downstream aspects of WCP were examined in MCL cell lines and tumors. Using WCP-spec...

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Autors principals: Gelebart, Pascal, Anand, Mona, Armanious, Hanan, Peters, Anthea C., Dien Bard, Jennifer, Amin, Hesham M., Lai, Raymond
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597612/
https://ncbi.nlm.nih.gov/pubmed/18787224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-02-139212
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