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Deciphering HIC1 control pathways to reveal new avenues in cancer therapeutics

INTRODUCTION: The tumor suppressor gene HIC1 (Hypermethylated in Cancer 1) which encodes a transcriptional repressor with multiple partners and multiple targets is epigenetically silenced but not mutated in tumors. HIC1 has broad biological roles during normal development and is implicated in many c...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: ROOD, Brian R., LEPRINCE, Dominique
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3683369/
https://ncbi.nlm.nih.gov/pubmed/23566242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/14728222.2013.788152
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