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Deciphering HIC1 control pathways to reveal new avenues in cancer therapeutics
INTRODUCTION: The tumor suppressor gene HIC1 (Hypermethylated in Cancer 1) which encodes a transcriptional repressor with multiple partners and multiple targets is epigenetically silenced but not mutated in tumors. HIC1 has broad biological roles during normal development and is implicated in many c...
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Format: | Artigo |
Sprache: | Inglês |
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2013
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Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3683369/ https://ncbi.nlm.nih.gov/pubmed/23566242 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/14728222.2013.788152 |
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