VCP is essential for mitochondrial quality control by PINK1/Parkin and this function is impaired by VCP mutations

Mutations in VCP cause multisystem degeneration impacting the nervous system, muscle, and/or bone. Patients may present with ALS, Parkinsonism, frontotemporal dementia, myopathy, Paget’s disease or a combination of these. The disease mechanism is unknown. We developed a Drosophila model of VCP mutat...

全面介紹

Na minha lista:
書目詳細資料
Main Authors: Kim, Nam Chul, Tresse, Emilie, Kolaitis, Regina M., Molliex, Amandine, Thomas, Ruth E., Alami, Nael H., Wang, Bo, Joshi, Aashish, Smith, Rebecca B., Ritson, Gillian P., Winborn, Brett J., Moore, Jennifer, Lee, Joo-Yong, Yao, Tso-Pang, Pallanck, Leo, Kundu, Mondira, Taylor, J. Paul
格式: Artigo
語言:Inglês
出版: 2013
主題:
Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3683300/
https://ncbi.nlm.nih.gov/pubmed/23498974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2013.02.029
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!

相似書籍