The Rho-GEF Trio regulates a novel pro-inflammatory pathway through the transcription factor Ets2

Inflammation is characterized by endothelium that highly expresses numerous adhesion molecules to trigger leukocyte extravasation. Central to this event is increased gene transcription. Small Rho-GTPases not only control the actin cytoskeleton, but are also implicated in gene regulation. However, in...

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Detalhes bibliográficos
Main Authors: Van Rijssel, Jos, Timmerman, Ilse, Van Alphen, Floris P. J., Hoogenboezem, Mark, Korchynskyi, Olexandr, Geerts, Dirk, Geissler, Judy, Reedquist, Kris A., Niessen, Hans W. M., Van Buul, Jaap D.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3683159/
https://ncbi.nlm.nih.gov/pubmed/23789107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.20134382
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