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The Rho-guanine nucleotide exchange factor Trio controls leukocyte transendothelial migration by promoting docking structure formation

Leukocyte transendothelial migration involves the active participation of the endothelium through the formation of apical membrane protrusions that embrace adherent leukocytes, termed docking structures. Using live-cell imaging, we find that prior to transmigration, endothelial docking structures fo...

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Autors principals: van Rijssel, Jos, Kroon, Jeffrey, Hoogenboezem, Mark, van Alphen, Floris P. J., de Jong, Renske J., Kostadinova, Elena, Geerts, Dirk, Hordijk, Peter L., van Buul, Jaap D.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3408411/
https://ncbi.nlm.nih.gov/pubmed/22696684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E11-11-0907
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