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Integral analysis of p53 and its value as prognostic factor in sporadic colon cancer
BACKGROUND: p53 (encoded by TP53) is involved in DNA damage repair, cell cycle regulation, apoptosis, aging and cellular senescence. TP53 is mutated in around 50% of human cancers. Nevertheless, the consequences of p53 inactivation in colon cancer outcome remain unclear. Recently, a new role of p53...
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| Główni autorzy: | , , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
BioMed Central
2013
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3682902/ https://ncbi.nlm.nih.gov/pubmed/23739040 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-13-277 |
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