Integral analysis of p53 and its value as prognostic factor in sporadic colon cancer

BACKGROUND: p53 (encoded by TP53) is involved in DNA damage repair, cell cycle regulation, apoptosis, aging and cellular senescence. TP53 is mutated in around 50% of human cancers. Nevertheless, the consequences of p53 inactivation in colon cancer outcome remain unclear. Recently, a new role of p53...

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Detalhes bibliográficos
Main Authors: Fariña Sarasqueta, Arantza, Forte, Giusi, Corver, Wim E, de Miranda, Noel F, Ruano, Dina, van Eijk, Ronald, Oosting, Jan, Tollenaar, Rob AEM, van Wezel, Tom, Morreau, Hans
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3682902/
https://ncbi.nlm.nih.gov/pubmed/23739040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-13-277
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