Loading...

An Amino-Benzosuberene Analogue That Inhibits Tubulin Assembly and Demonstrates Remarkable Cytotoxicity

The recent discovery of a small-molecule benzosuberene-based phenol that demonstrates remarkable picomolar cytotoxicity against selected human cancer cell lines and strongly inhibits tubulin polymerization (1–2 µM) inspired the design and synthesis of a variety of new, structurally diverse benzosube...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Tanpure, Rajendra P., George, Clinton S., Sriram, Madhavi, Strecker, Tracy E., Tidmore, Justin K., Hamel, Ernest, Charlton-Sevcik, Amanda K., Chaplin, David J., Trawick, Mary Lynn, Pinney, Kevin G.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3682772/
https://ncbi.nlm.nih.gov/pubmed/23772309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C2MD00318J
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!