High-resolution analysis of cis-acting regulatory networks at the α-globin locus

We have combined the circular chromosome conformation capture protocol with high-throughput, genome-wide sequence analysis to characterize the cis-acting regulatory network at a single locus. In contrast to methods which identify large interacting regions (10–1000 kb), the 4C approach provides a com...

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Main Authors: Hughes, Jim R., Lower, Karen M., Dunham, Ian, Taylor, Stephen, De Gobbi, Marco, Sloane-Stanley, Jacqueline A., McGowan, Simon, Ragoussis, Jiannis, Vernimmen, Douglas, Gibbons, Richard J., Higgs, Douglas R.
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2013
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3682726/
https://ncbi.nlm.nih.gov/pubmed/23650635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2012.0361
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