Glycogen synthase kinase-3 (GSK-3) regulates TGF-β(1)-induced differentiation of pulmonary fibroblasts

BACKGROUND: Chronic lung diseases such as asthma, COPD and pulmonary fibrosis are characterized by abnormal extracellular matrix (ECM) turnover. TGF-β is a key mediator stimulating ECM production by recruiting and activating lung fibroblasts and initiating their differentiation process into more act...

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Detalhes bibliográficos
Main Authors: Baarsma, Hoeke A, Engelbertink, Lilian HJM, van Hees, Lonneke J, Menzen, Mark H, Meurs, Herman, Timens, Wim, Postma, Dirkje S, Kerstjens, Huib AM, Gosens, Reinoud
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2013
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3682707/
https://ncbi.nlm.nih.gov/pubmed/23297769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12098
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