Induction of autoantibodies against lung matrix proteins and smoke-induced inflammation in mice

BACKGROUND: Smoking is the major etiologic factor in COPD, yet the exact underlying pathogenetic mechanisms have not been elucidated. Since a few years, there is mounting evidence that a specific immune response, partly present as an autoimmune response, contributes to the pathogenesis of COPD. Incr...

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Main Authors: Brandsma, Corry-Anke, Timens, Wim, Geerlings, Marie, Jekel, Henrike, Postma, Dirkje S, Hylkema, Machteld N, Kerstjens, Huib AM
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2010
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3019146/
https://ncbi.nlm.nih.gov/pubmed/21144028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2466-10-64
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