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Heme oxygenase-1 prevents smoke induced B-cell infiltrates: a role for regulatory T cells?

BACKGROUND: Smoking is the most important cause for the development of COPD. Since not all smokers develop COPD, it is obvious that other factors must be involved in disease development. We hypothesize that heme oxygenase-1 (HO-1), a protective enzyme against oxidative stress and inflammation, is in...

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Detalhes bibliográficos
Main Authors: Brandsma, Corry-Anke, Hylkema, Machteld N, van der Strate, Barry WA, Slebos, Dirk-Jan, Luinge, Marjan A, Geerlings, Marie, Timens, Wim, Postma, Dirkje S, Kerstjens, Huib AM
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2254411/
https://ncbi.nlm.nih.gov/pubmed/18252008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-9-17
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