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Proteasomal Degradation of Eukaryotic Elongation Factor-2 Kinase (EF2K) Is Regulated by cAMP-PKA Signaling and the SCF(βTRCP) Ubiquitin E3 Ligase

Protein translation and degradation are critical for proper protein homeostasis, yet it remains unclear how these processes are dynamically regulated, or how they may directly balance or synergize with each other. An important translational control mechanism is the Ca(2+)/calmodulin-dependent phosph...

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Detalhes bibliográficos
Main Authors: Wiseman, Shari L., Shimizu, Yoshio, Palfrey, Clive, Nairn, Angus C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3682579/
https://ncbi.nlm.nih.gov/pubmed/23640883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.477182
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