Exosome Uptake Depends on ERK1/2-Heat Shock Protein 27 Signaling and Lipid Raft-mediated Endocytosis Negatively Regulated by Caveolin-1

The role of exosomes in cancer can be inferred from the observation that they transfer tumor cell derived genetic material and signaling proteins, resulting in e.g. increased tumor angiogenesis and metastasis. However, the membrane transport mechanisms and the signaling events involved in the uptake...

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Bibliografiske detaljer
Main Authors:	Svensson, Katrin J., Christianson, Helena C., Wittrup, Anders, Bourseau-Guilmain, Erika, Lindqvist, Eva, Svensson, Lena M., Mörgelin, Matthias, Belting, Mattias
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Biochemistry and Molecular Biology 2013
Fag:	Cell Biology
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3682571/ https://ncbi.nlm.nih.gov/pubmed/23653359 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.445403
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Exosome Uptake Depends on ERK1/2-Heat Shock Protein 27 Signaling and Lipid Raft-mediated Endocytosis Negatively Regulated by Caveolin-1

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