The Mechanism of Polyplexes Internalization into Cells: Testing the GM1/Caveolin-1-Mediated Lipid Raft Mediated Endocytosis Pathway

The GM1/caveolin-1 lipid raft mediated endocytosis mechanism was explored for generation 5 and 7 poly(amidoamine) dendrimer polyplexes employing the Cos-7, 293A, C6, HeLa, KB, and HepG2 cell lines. Expression levels of GM1 and caveolin-1 were measured using Dot Blot and Western Blot, respectively. T...

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Hlavní autoři: Qi, Rong, Mullen, Douglas G., Baker, James R., Banaszak Holl, Mark M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2826151/
https://ncbi.nlm.nih.gov/pubmed/20025295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp900241t
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