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Unusual Cytochrome P450 Enzymes and Reactions

Cytochrome P450 enzymes primarily catalyze mixed-function oxidation reactions, plus some reductions and rearrangements of oxygenated species, e.g. prostaglandins. Most of these reactions can be rationalized in a paradigm involving Compound I, a high-valent iron-oxygen complex (FeO(3+)), to explain s...

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Hlavní autoři: Guengerich, F. Peter, Munro, Andrew W.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3682512/
https://ncbi.nlm.nih.gov/pubmed/23632016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R113.462275
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