Ablation of Kappa-Opioid Receptors from Brain Dopamine Neurons has Anxiolytic-Like Effects and Enhances Cocaine-Induced Plasticity

Brain kappa-opioid receptors (KORs) are implicated in states of motivation and emotion. Activation of KORs negatively regulates mesolimbic dopamine (DA) neurons, and KOR agonists produce depressive-like behavioral effects. To further evaluate how KOR function affects behavior, we developed mutant mi...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Van't Veer, Ashlee, Bechtholt, Anita J, Onvani, Sara, Potter, David, Wang, Yujun, Liu-Chen, Lee-Yuan, Schütz, Günther, Chartoff, Elena H, Rudolph, Uwe, Cohen, Bruce M, Carlezon, William A
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2013
Assuntos:
Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3682153/
https://ncbi.nlm.nih.gov/pubmed/23446450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2013.58
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares