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Pancreatic α-Cell Specific Deletion of Mouse Arx Leads to α-Cell Identity Loss
The specification and differentiation of pancreatic endocrine cell populations (α-, β-, δ, PP- and ε-cells) is orchestrated by a combination of transcriptional regulators. In the pancreas, Aristaless-related homeobox gene (Arx) is expressed first in the endocrine progenitors and then restricted to g...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3681972/ https://ncbi.nlm.nih.gov/pubmed/23785486 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0066214 |
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