Discovery of the novel mTOR inhibitor and its antitumor activities in vitro and in vivo

The phosphatidylinositol 3-kinase (PI3-K)/Akt and mammalian target of rapamycin (mTOR) signaling pathway plays a critical role in cell survival and proliferation and is often aberrantly activated in many types of cancer. The mTOR kinase protein, one of the key molecules in this pathway, has been sho...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Xie, Hua, Lee, Mee-Hyun, Zhu, Feng, Reddy, Kanamata, Huang, Zunnan, Kim, Dong Joon, Li, Yan, Peng, Cong, Lim, Do Young, Kang, Soouk, Jung, Sung Keun, Li, Xiang, Li, Haitao, Ma, Weiya, Lubet, Ronald A., Ding, Jian, Bode, Ann M., Dong, Zigang
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
Materias:
Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3681861/
https://ncbi.nlm.nih.gov/pubmed/23536724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-12-1241
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares