The Adjuvant Activity of Alphavirus Replicons Is Enhanced by Incorporating the Microbial Molecule Flagellin into the Replicon

Ligands of pattern recognition receptors (PRRs) including Toll-like receptors (TLRs) stimulate innate and adaptive immune responses and are considered as potent adjuvants. Combinations of ligands might act in synergy to induce stronger and broader immune responses compared to stand-alone ligands. Al...

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Detaylı Bibliyografya
Asıl Yazarlar: Knudsen, Maria L., Johansson, Daniel X., Kostic, Linda, Nordström, Eva K. L., Tegerstedt, Karin, Pasetto, Anna, Applequist, Steven E., Ljungberg, Karl, Sirard, Jean-Claude, Liljeström, Peter
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2013
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3681802/
https://ncbi.nlm.nih.gov/pubmed/23785460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0065964
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