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Nebulin binding impedes mutant desmin filament assembly

Desmin intermediate filaments (DIFs) form an intricate meshwork that organizes myofibers within striated muscle cells. The mechanisms that regulate the association of desmin to sarcomeres and their role in desminopathy are incompletely understood. Here we compare the effect nebulin binding has on th...

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Autors principals: Baker, Laura K., Gillis, David C., Sharma, Sarika, Ambrus, Andy, Herrmann, Harald, Conover, Gloria M.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3681697/
https://ncbi.nlm.nih.gov/pubmed/23615443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E12-11-0840
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