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Severe muscle disease-causing desmin mutations interfere with in vitro filament assembly at distinct stages
Desmin is the major intermediate filament (IF) protein of muscle. Recently, mutations of the desmin gene have been reported to cause familial or sporadic forms of human skeletal, as well as cardiac, myopathy, termed desmin-related myopathy (DRM). The impact of any of these mutations on filament asse...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1250230/ https://ncbi.nlm.nih.gov/pubmed/16217025 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0504568102 |
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