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αB-crystallin is a sensor for assembly intermediates and for the subunit topology of desmin intermediate filaments

Mutations in the small heat shock protein chaperone CRYAB (αB-crystallin/HSPB5) and the intermediate filament protein desmin, phenocopy each other causing cardiomyopathies. Whilst the binding sites for desmin on CRYAB have been determined, desmin epitopes responsible for CRYAB binding and also the p...

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Bibliografiska uppgifter
I publikationen:Cell Stress Chaperones
Huvudupphovsmän: Sharma, Sarika, Conover, Gloria M., Elliott, Jayne L., Der Perng, Ming, Herrmann, Harald, Quinlan, Roy A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Springer Netherlands 2017
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5465037/
https://ncbi.nlm.nih.gov/pubmed/28470624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-017-0788-7
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