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αB-crystallin is a sensor for assembly intermediates and for the subunit topology of desmin intermediate filaments

Mutations in the small heat shock protein chaperone CRYAB (αB-crystallin/HSPB5) and the intermediate filament protein desmin, phenocopy each other causing cardiomyopathies. Whilst the binding sites for desmin on CRYAB have been determined, desmin epitopes responsible for CRYAB binding and also the p...

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Detalhes bibliográficos
Publicado no:Cell Stress Chaperones
Main Authors: Sharma, Sarika, Conover, Gloria M., Elliott, Jayne L., Der Perng, Ming, Herrmann, Harald, Quinlan, Roy A.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5465037/
https://ncbi.nlm.nih.gov/pubmed/28470624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-017-0788-7
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