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αB-crystallin is a sensor for assembly intermediates and for the subunit topology of desmin intermediate filaments

Mutations in the small heat shock protein chaperone CRYAB (αB-crystallin/HSPB5) and the intermediate filament protein desmin, phenocopy each other causing cardiomyopathies. Whilst the binding sites for desmin on CRYAB have been determined, desmin epitopes responsible for CRYAB binding and also the p...

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Foilsithe in:Cell Stress Chaperones
Main Authors: Sharma, Sarika, Conover, Gloria M., Elliott, Jayne L., Der Perng, Ming, Herrmann, Harald, Quinlan, Roy A.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Springer Netherlands 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5465037/
https://ncbi.nlm.nih.gov/pubmed/28470624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-017-0788-7
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