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αB-crystallin is a sensor for assembly intermediates and for the subunit topology of desmin intermediate filaments

Mutations in the small heat shock protein chaperone CRYAB (αB-crystallin/HSPB5) and the intermediate filament protein desmin, phenocopy each other causing cardiomyopathies. Whilst the binding sites for desmin on CRYAB have been determined, desmin epitopes responsible for CRYAB binding and also the p...

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Dades bibliogràfiques
Publicat a:Cell Stress Chaperones
Autors principals: Sharma, Sarika, Conover, Gloria M., Elliott, Jayne L., Der Perng, Ming, Herrmann, Harald, Quinlan, Roy A.
Format: Artigo
Idioma:Inglês
Publicat: Springer Netherlands 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5465037/
https://ncbi.nlm.nih.gov/pubmed/28470624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-017-0788-7
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