The specificity of the interaction between αB-crystallin and desmin filaments and its impact on filament aggregation and cell viability

CRYAB (αB-crystallin) is expressed in many tissues and yet the R120G mutation in CRYAB causes tissue-specific pathologies, namely cardiomyopathy and cataract. Here, we present evidence to demonstrate that there is a specific functional interaction of CRYAB with desmin intermediate filaments that pre...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Elliott, Jayne L., Der Perng, Ming, Prescott, Alan R., Jansen, Karin A., Koenderink, Gijsje H., Quinlan, Roy A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2013
Assuntos:
Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3638400/
https://ncbi.nlm.nih.gov/pubmed/23530264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2012.0375
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados