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Engineering fungal non-reducing polyketide synthase by heterologous expression and domain swapping
[Image: see text] We re-annotated the A. niger NR-PKS gene, e_gw1_19.204 and its downstream R domain gene, est_GWPlus_C_190476 as a single gene which we name dtbA. Heterologous expression of dtbA in A. nidulans demonstrated that DtbA protein produces two polyketides, 2,4-dihydroxy-3,5,6-trimethylben...
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| Main Authors: | , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2013
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3681297/ https://ncbi.nlm.nih.gov/pubmed/23368695 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol303328t |
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