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Upregulated insulin secretion in insulin-resistant mice: evidence of increased islet GLP1 receptor levels and GPR119-activated GLP1 secretion

We previously demonstrated that the overall incretin effect and the β-cell responsiveness to glucagon-like peptide-1 (GLP1) are increased in insulin-resistant mice and may contribute to the upregulated β-cell function. Now we examined whether this could, first, be explained by increased islet GLP1 r...

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Библиографические подробности
Главные авторы: Ahlkvist, L, Brown, K, Ahrén, B
Формат: Artigo
Язык:Inglês
Опубликовано: BioScientifica 2013
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3680955/
https://ncbi.nlm.nih.gov/pubmed/23781322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/EC-12-0079
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