Agonists at GPR119 mediate secretion of GLP-1 from mouse enteroendocrine cells through glucose-independent pathways

BACKGROUND AND PURPOSE: The G protein-coupled receptor 119 (GPR119) mediates insulin secretion from pancreatic β cells and glucagon-like peptide 1 (GLP-1) release from intestinal L cells. While GPR119-mediated insulin secretion is glucose dependent, it is not clear whether or not GPR119-mediated GLP...

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Detalhes bibliográficos
Main Authors: Lan, H, Lin, HV, Wang, CF, Wright, MJ, Xu, S, Kang, L, Juhl, K, Hedrick, JA, Kowalski, TJ
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2012
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3423251/
https://ncbi.nlm.nih.gov/pubmed/22029751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2011.01754.x
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