Ciliary subcellular localization of TGR5 determines the cholangiocyte functional response to bile acid signaling

TGR5, the G protein-coupled bile acid receptor that transmits bile acid signaling into a cell functional response via the intracellular cAMP signaling pathway, is expressed in human and rodent cholangiocytes. However, detailed information on the localization and function of cholangiocyte TGR5 is lim...

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Detalhes bibliográficos
Main Authors: Masyuk, Anatoliy I., Huang, Bing Q., Radtke, Brynn N., Gajdos, Gabriella B., Splinter, Patrick L., Masyuk, Tatyana V., Gradilone, Sergio A., LaRusso, Nicholas F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2013
Assuntos:
Liver and Biliary Tract
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3680685/
https://ncbi.nlm.nih.gov/pubmed/23578785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00383.2012
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