Cholangiocyte primary cilia are chemosensory organelles that detect biliary nucleotides via P2Y(12) purinergic receptors

Cholangiocytes, the epithelial cells lining intrahepatic bile ducts, contain primary cilia, which are mechano- and osmosensory organelles detecting changes in bile flow and osmolality and transducing them into intracellular signals. Here, we asked whether cholangiocyte cilia are chemosensory organel...

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Detalhes bibliográficos
Main Authors: Masyuk, Anatoliy I., Gradilone, Sergio A., Banales, Jesus M., Huang, Bing Q., Masyuk, Tatyana V., Lee, Seung-Ok, Splinter, Patrick L., Stroope, Angela J., LaRusso, Nicholas F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2008
Assuntos:
Liver and Biliary Tract
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2575915/
https://ncbi.nlm.nih.gov/pubmed/18687752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.90265.2008
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