Comprehensive Experimental and Computational Analysis of Binding Energy Hot Spots at the NF-κB Essential Modulator (NEMO)/IKKβ Protein-Protein Interface

We report a comprehensive analysis of binding energy hot spots at the protein-protein interaction (PPI) interface between NF-κB Essential Modulator (NEMO) and IκB kinase subunit β (IKKβ), an interaction that is critical for NF-κB pathway signaling, using experimental alanine scanning mutagenesis and...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Golden, Mary S., Cote, Shaun M., Sayeg, Marianna, Zerbe, Brandon S., Villar, Elizabeth A., Beglov, Dmitri, Sazinsky, Stephen L., Georgiadis, Rosina M., Vajda, Sandor, Kozakov, Dima, Whitty, Adrian
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2013
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3680600/
https://ncbi.nlm.nih.gov/pubmed/23506214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja400914z
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg