Densely Granulated Murine NK Cells Eradicate Large Solid Tumors

NK cells inhibit early stages of tumor formation, recurrence and metastasis. Here we show that NK cells can also eradicate large solid tumors. Eradication depended on the massive infiltration of proliferating NK cells due to IL15 released and presented by the cancer cells in the tumor microenvironme...

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Detalhes bibliográficos
Main Authors: Liu, Rebecca B., Engels, Boris, Arina, Ainhoa, Schreiber, Karin, Hyjek, Elizabeth, Schietinger, Andrea, Binder, David C., Butz, Eric, Krausz, Thomas, Rowley, Donald A., Jabri, Bana, Schreiber, Hans
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3680344/
https://ncbi.nlm.nih.gov/pubmed/22374983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-3208
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