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Modular, rule-based modeling for the design of eukaryotic synthetic gene circuits

BACKGROUND: The modular design of synthetic gene circuits via composable parts (DNA segments) and pools of signal carriers (molecules such as RNA polymerases and ribosomes) has been successfully applied to bacterial systems. However, eukaryotic cells are becoming a preferential host for new syntheti...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Marchisio, Mario Andrea, Colaiacovo, Moreno, Whitehead, Ellis, Stelling, Jörg
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3680069/
https://ncbi.nlm.nih.gov/pubmed/23705868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-7-42
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