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Automatic Design of Digital Synthetic Gene Circuits

De novo computational design of synthetic gene circuits that achieve well-defined target functions is a hard task. Existing, brute-force approaches run optimization algorithms on the structure and on the kinetic parameter values of the network. However, more direct rational methods for automatic cir...

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Bibliografiske detaljer
Main Authors: Marchisio, Mario A., Stelling, Jörg
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048778/
https://ncbi.nlm.nih.gov/pubmed/21399700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1001083
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