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Modular, rule-based modeling for the design of eukaryotic synthetic gene circuits

BACKGROUND: The modular design of synthetic gene circuits via composable parts (DNA segments) and pools of signal carriers (molecules such as RNA polymerases and ribosomes) has been successfully applied to bacterial systems. However, eukaryotic cells are becoming a preferential host for new syntheti...

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Detalhes bibliográficos
Main Authors: Marchisio, Mario Andrea, Colaiacovo, Moreno, Whitehead, Ellis, Stelling, Jörg
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3680069/
https://ncbi.nlm.nih.gov/pubmed/23705868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-7-42
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