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Modular, rule-based modeling for the design of eukaryotic synthetic gene circuits

BACKGROUND: The modular design of synthetic gene circuits via composable parts (DNA segments) and pools of signal carriers (molecules such as RNA polymerases and ribosomes) has been successfully applied to bacterial systems. However, eukaryotic cells are becoming a preferential host for new syntheti...

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Bibliografske podrobnosti
Main Authors: Marchisio, Mario Andrea, Colaiacovo, Moreno, Whitehead, Ellis, Stelling, Jörg
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3680069/
https://ncbi.nlm.nih.gov/pubmed/23705868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-7-42
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