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Modular, rule-based modeling for the design of eukaryotic synthetic gene circuits

BACKGROUND: The modular design of synthetic gene circuits via composable parts (DNA segments) and pools of signal carriers (molecules such as RNA polymerases and ribosomes) has been successfully applied to bacterial systems. However, eukaryotic cells are becoming a preferential host for new syntheti...

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Autori principali: Marchisio, Mario Andrea, Colaiacovo, Moreno, Whitehead, Ellis, Stelling, Jörg
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3680069/
https://ncbi.nlm.nih.gov/pubmed/23705868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-7-42
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