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Mahogunin ring finger-1 (MGRN1) Suppresses Chaperone-Associated Misfolded Protein Aggregation and Toxicity

Impairment in the elimination of misfolded proteins generates cellular toxicity and leads to various late-onset neurodegenerative diseases. However, the mechanisms by which cells recognize abnormal cellular proteins for selective clearance remain unknown. Lack of the mahogunin ring finger-1 (MGRN1)...

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Main Authors: Chhangani, Deepak, Mishra, Amit
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3679506/
https://ncbi.nlm.nih.gov/pubmed/23756845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep01972
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