Non-canonical kinase signaling by the death ligand TRAIL in cancer cells: discord in the death receptor family

Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-based therapy is currently evaluated in clinical studies as a tumor cell selective pro-apoptotic approach. However, besides activating canonical caspase-dependent apoptosis by binding to TRAIL-specific death receptors, the TRAIL ligand...

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Bibliografiske detaljer
Main Authors: Azijli, K, Weyhenmeyer, B, Peters, G J, de Jong, S, Kruyt, F A E
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2013
Fag:
Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3679459/
https://ncbi.nlm.nih.gov/pubmed/23579241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2013.28
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