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Non-canonical kinase signaling by the death ligand TRAIL in cancer cells: discord in the death receptor family
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-based therapy is currently evaluated in clinical studies as a tumor cell selective pro-apoptotic approach. However, besides activating canonical caspase-dependent apoptosis by binding to TRAIL-specific death receptors, the TRAIL ligand...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3679459/ https://ncbi.nlm.nih.gov/pubmed/23579241 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2013.28 |
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