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Structural significance of the GTP-binding domain of ras p21 studied by site-directed mutagenesis.

Point mutations of p21 proteins were constructed by oligonucleotide-directed mutagenesis of the v-rasH oncogene, which substituted amino acid residues within the nucleotide-binding consensus sequence, GXG GXGK. When the glycine residue at position 10, 13, or 15 was substituted with valine, the viral...

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Udgivet i:Mol Cell Biol
Principais autores: Clanton, D J, Lu, Y Y, Blair, D G, Shih, T Y
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 1987
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC367941/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3118192/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.7.9.3092-3097.1987
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