Rare APOA5 promoter variants associated with paradoxical HDL cholesterol decrease in response to fenofibric acid therapy

Individuals with mixed dyslipidemia, including high triglycerides (TGs) and low high density lipoprotein cholesterol (HDL-C), have increased risk for coronary events. We examined the effect of rare genetic variants in the APOA5 gene region on plasma HDL-C, apolipoprotein A-I (apoA-I), and TG respons...

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Bibliographische Detailangaben
Hauptverfasser: Brautbar, Ariel, Barbalic, Maja, Chen, Fengju, Belmont, John, Virani, Salim S., Scherer, Steve, Hegele, Robert A., Ballantyne, Christie M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Biochemistry and Molecular Biology 2013
Schlagworte:
Patient-Oriented and Epidemiological Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3679399/
https://ncbi.nlm.nih.gov/pubmed/23633496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M034132
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