Interaction between SNPs in the RXRA and near ANGPTL3 gene region inhibits apoB reduction after statin-fenofibric acid therapy in individuals with mixed dyslipidemia

The mixed dyslipidemia phenotype is characterized by elevated triglycerides (TG), low HDL cholesterol (HDL-C), increased ApoB levels, and premature coronary atherosclerosis. Fibrate-statin combination therapy reduces ApoB levels and coronary events in the mixed dyslipidemia population. We sought to...

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Bibliographic Details
Main Authors: Ma, Li, Ballantyne, Christie M., Belmont, John W., Keinan, Alon, Brautbar, Ariel
Format: Artigo
Language:Inglês
Published: The American Society for Biochemistry and Molecular Biology 2012
Subjects:
Patient-Oriented and Epidemiological Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3466010/
https://ncbi.nlm.nih.gov/pubmed/22896670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M028829
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