Rare LPL gene variants attenuate triglyceride reduction and HDL cholesterol increase in response to fenofibric acid therapy in individuals with mixed dyslipidemia

OBJECTIVE: Individuals with mixed dyslipidemia have elevated triglycerides (TG), low high-density lipo-protein cholesterol (HDL-C), and increased risk for coronary disease. Fibrate therapy is commonly used to lower TG and increase HDL-C. Common genetic variants are known to affect the response to fi...

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Hauptverfasser: Gao, Feng, Ballantyne, Christie, Ma, Li, Virani, Salim S., Keinan, Alon, Brautbar, Ariel
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4078400/
https://ncbi.nlm.nih.gov/pubmed/24704626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.atherosclerosis.2014.03.010
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