Adiponectin regulates bone mass accrual through two opposite mechanisms, one local and one central, that both rely on FoxO1

The synthesis of adiponectin, an adipokine with ill-defined functions in animals fed a normal diet, is enhanced by the osteoblast-derived hormone osteocalcin. Here we show that adiponectin signals back in osteoblasts to hamper their proliferation and favor their apoptosis, altogether decreasing bone...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Kajimura, Daisuke, Lee, Ha Won, Riley, Kyle J., Arteaga-Solis, Emilio, Ferron, Mathieu, Zhou, Bin, Clarke, Christopher J., Hannun, Yusuf A., DePinho, Ronald A, Guo, Edward X., Mann, J. John, Karsenty, Gerard
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2013
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3679303/
https://ncbi.nlm.nih.gov/pubmed/23684624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2013.04.009
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller