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Mammalian PIK3C3/VPS34: The key to autophagic processing in liver and heart
PIK3C3/Vps34 is the class III PtdIns3K that is evolutionarily conserved from yeast to mammals. Its central role in mammalian autophagy has been suggested through the use of pharmacological inhibitors and the study of its binding partners. However, the precise role of PIK3C3 in mammals is not clear....
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Landes Bioscience
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3679090/ https://ncbi.nlm.nih.gov/pubmed/22498475 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.19627 |
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